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1. Describe the metabolic fates of phenylalanine; highlighting the synthesis and degradation pathways of catecholamines (dopamine, norepinephrine, and epinephrine), melanin, and thyroid hormones.2. Describe the biochemical relationships between these disease and phenylalanine metabolism; albinism, phenylketonuria, Parkinson’s disease, and Haloperidol toxicity.3. Describe the pharmacological importance of the enzymes COMT and MAO.4. How can a knowledge of phenylalanine metabolism be useful in the laboratory diagnosis of pheochromocytoma?
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