Respond to your colleagues on and respectfully agree or disagree with your colleague’s assessment and explain your reasoning. In your explanation, include why their explanations make physiological sense or why they do not. Include 2 scholars sources, cited within the reply: Several studies have shown that allergies are hereditary, children are 75% more likely to have allergies if both parents have them, and 50% likely to have them if one parent has them(Brooten-Brooks, 2021). Atopy is a predisposition to various allergens and antigens leading to an overproduction of immunoglobulin E, which produces heightened, hypersensitivity reactions(Vaillant, 2023). This patient appears to be presenting with a severe allergic reaction that could rapidly lead to anaphylaxis, if not rapidly treated. The symptoms that the patient is exhibiting is indicative of vasodilation, which is why the systolic blood pressure is low and the heart rate is high. Vasodilation occurs in response to anaphylactic shock due to a rapid release of inflammatory mediators and cytokines(Ramanlal, 2023). The drop in blood pressure, nausea, and difficulty swallowing are occurring due to the release of histamine and vasodilation. The activation of basophils and mast cells causes an immediate release of mediators from secretory granules that include histamine, which in turn stimulates vasodilation, increased heart rate, vascular permeability, cardiac contraction, and glandular secretion(Nguyen et al., 2021). The allergic reaction, while genetics may play a factor, it could also be exacerbated other factors like specific diseases, medical disorders, environmental factors, or medications. Also, interestingly, Anaphylaxis in general, is more common in adult females than in males, a predominance that appears after puberty(De Martinis et al., 2020). Allergic reactions are complex and very prevalent in today’s society. according to the Allergy and Asthma Network, one in twenty Americans have experienced anaphylaxis(Anaphylaxis statistics 2024).
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